Vaping Impairs Vascular Function, Even Without Nicotine, Study Finds Can Smoking and Vaping Cause Back Pain? National Spine Health Foundation Vaping delivers heated chemicals directly into the lungs. Unlike air, vape aerosols contain fine particles, nicotine, heavy metals, and flavoring compounds that were never designed to be inhaled. Once inside the chest, What Does Vaping Do to Your Lungs? Johns Hopkins Medicine UCLA study finds even short term vaping poses significant risk to health Daily Bruin Vaping can have serious negative impacts on both your lungs and your overall health. Here are the potential risks that we already know about, even if the vape is nicotine free: